We AI-M to transform research, diagnosis, and treatment in psychiatry by advancing neuroscience-informed, responsible artificial intelligence.

The University of Toronto hosts a joint program through the Department of Psychiatry, the Interventional Psychiatry Program at St. Michael’s Hospital (Unity Health Toronto), and University Health Network, aiming to develop and integrate safe and responsible artificial intelligence to support mental health care, research, and innovation – always with compassionate patient care at the centre of our work.

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		[{"id":2972,"link":"https:\/\/ai.psychiatry.utoronto.ca\/new-publication-in-npj-digital-medicine\/","name":"new-publication-in-npj-digital-medicine","thumbnail":{"url":"https:\/\/ai.psychiatry.utoronto.ca\/wp-content\/uploads\/2026\/02\/Screenshot-2026-02-23-at-12.51.20-PM.png","alt":""},"title":"New Publication in npj Digital Medicine","postMeta":[],"author":{"name":"vbhat","link":"https:\/\/ai.psychiatry.utoronto.ca\/author\/vbhat\/"},"date":"Feb 23, 2026","dateGMT":"2026-02-23 17:06:29","modifiedDate":"2026-02-23 13:15:27","modifiedDateGMT":"2026-02-23 18:15:27","commentCount":"0","commentStatus":"open","categories":{"coma":"<a href=\"https:\/\/ai.psychiatry.utoronto.ca\/category\/publications\/\" rel=\"category tag\">Publications<\/a>","space":"<a href=\"https:\/\/ai.psychiatry.utoronto.ca\/category\/publications\/\" rel=\"category tag\">Publications<\/a>"},"taxonomies":{"post_tag":""},"readTime":{"min":1,"sec":33},"status":"publish","content":"Teferra et al. (2026) systematically evaluated how safety guardrails influence the affective outputs of large language models (LLMs), operationalizing irritability as a measurable behavioral construct. Using validated psychometric instruments adapted for model assessment, the team compared multiple contemporary LLMs under varying safety configurations"}]